mouse TNIP3 Over-expression AAV

Name 
AAV-m-TNIP3
Cat No 
AAV-274747
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Tnip3.

AAV-274747
AAV-m-TNIP3

Ready-to-use AAV expressing Mouse Tnip3 (TNFAIP3 interacting protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9030611K07Rik; ABIN-3; LIND
Description (Vector)
Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
Gene ID
414084
Gene Name (Vector)
TNFAIP3 interacting protein 3
Gene Symbol
Tnip3
ORF Size (aa)
627
ORF Size (bp)
627 bp
RefSeq ID
NM_001001495
RefSeq Synonyms
NM_001001495, BC104393,
Species
mouse
UniGene ID
Mm.117558

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.