mouse TNIP3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tnip3.
shAAV-274747
AAV-m-TNIP3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tnip3 (TNFAIP3 interacting protein 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9030611K07Rik; ABIN-3; LIND
Description (Vector)
Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
Gene ID
414084
Gene Name (Vector)
TNFAIP3 interacting protein 3
Gene Symbol
Tnip3
ORF Size (aa)
627
ORF Size (bp)
627 bp
RefSeq ID
NM_001001495
RefSeq Synonyms
NM_001001495, BC104393,
Species
mouse
UniGene ID
Mm.117558
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.