mouse TMEM173 Over-expression AAV

Name 
AAV-m-TMEM173
Cat No 
AAV-274453
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Tmem173.

AAV-274453
AAV-m-TMEM173

Ready-to-use AAV expressing Mouse Tmem173 (transmembrane protein 173). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2610307O08Rik; ERIS; Mita; MPYS; STING
Description (Vector)
Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
Gene ID
72512
Gene Name (Vector)
transmembrane protein 173
Gene Symbol
Tmem173
ORF Size (aa)
1137
ORF Size (bp)
1137 bp
RefSeq ID
NM_028261
RefSeq Synonyms
NM_028261, NM_001289592, NM_001289591, BC046640,
Species
mouse
UniGene ID
Mm.45995

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.