mouse TLR7 Over-expression AAV
This is an AAV expressing Mouse Tlr7.
AAV-274285
AAV-m-TLR7
Ready-to-use AAV expressing Mouse Tlr7 (toll-like receptor 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Gene ID
170743
Gene Name (Vector)
toll-like receptor 7
Gene Symbol
Tlr7
ORF Size (aa)
3153
ORF Size (bp)
3153 bp
RefSeq ID
NM_133211
RefSeq Synonyms
NM_133211, NM_001290758, NM_001290757, NM_001290756, NM_001290755, BC132385, BC120596,
Species
mouse
UniGene ID
Mm.23979
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.