mouse TEAD3 Over-expression AAV

Name 
AAV-m-TEAD3
Cat No 
AAV-274006
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Tead3.

AAV-274006
AAV-m-TEAD3

Ready-to-use AAV expressing Mouse Tead3 (TEA domain family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DTEF-1; ETFR-1; Tcf13r2; TEAD-3; TEF-5
Description (Vector)
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
Gene ID
21678
Gene Name (Vector)
TEA domain family member 3
Gene Symbol
Tead3
ORF Size (aa)
1395
ORF Size (bp)
1395 bp
RefSeq ID
NM_011566
RefSeq Synonyms
NM_011566, NM_001204156, NM_001098226, BC156574, BC146313,
Species
mouse
UniGene ID
Mm.6655

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.