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mouse TCFE3 Over-expression AAV

Name 
AAV-m-TCFE3
Cat No 
AAV-273940
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Tfe3.

AAV-273940
AAV-m-TCFE3

Ready-to-use AAV expressing Mouse Tfe3 (transcription factor E3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bHLHe33; F830016E06Rik; Tcfe3; Tfe-3
Description (Vector)
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Gene ID
209446
Gene Name (Vector)
transcription factor E3
Gene Symbol
Tfe3
ORF Size (aa)
1719
ORF Size (bp)
1719 bp
RefSeq ID
NM_172472
RefSeq Synonyms
NM_172472, NM_001271491, NM_001271490, NM_001271489, NM_001105197, NM_001105196, BC063047, BC056358,
Species
mouse
UniGene ID
Mm.249142

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.