mouse STRAP Over-expression AAV

Name 
AAV-m-STRAP
Cat No 
AAV-273385
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Strap.

AAV-273385
AAV-m-STRAP

Ready-to-use AAV expressing Mouse Strap (serine/threonine kinase receptor associated protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AW557906; C78091; C79202; Unrip
Description (Vector)
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
Gene ID
20901
Gene Name (Vector)
serine/threonine kinase receptor associated protein
Gene Symbol
Strap
ORF Size (aa)
1053
RefSeq ID
NM_011499
RefSeq Synonyms
NM_011499, BC145342, BC141076,
Species
mouse
UniGene ID
Mm.22584

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.