rat STRAP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Strap.
shAAV-291381
AAV-r-STRAP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Strap (serine/threonine kinase receptor associated protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
Gene ID
297699
Gene Name (Vector)
serine/threonine kinase receptor associated protein
Gene Symbol
Strap
ORF Size (aa)
1053
RefSeq ID
NM_001011969
RefSeq Synonyms
NM_001011969, BC083714,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.