mouse SPIB Over-expression AAV

Name 
AAV-m-SPIB
Cat No 
AAV-273001
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Spib.

AAV-273001
AAV-m-SPIB

Ready-to-use AAV expressing Mouse Spib (Spi-B transcription factor (Spi-1/PU.1 related)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Spi-B
Description (Vector)
Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation.
Gene ID
272382
Gene Name (Vector)
Spi-B transcription factor (Spi-1/PU.1 related)
Gene Symbol
Spib
ORF Size (aa)
804
RefSeq ID
NM_019866
RefSeq Synonyms
NM_019866, BC141118,
Species
mouse
UniGene ID
Mm.8012

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.