mouse SMPD2 Over-expression AAV

Name 
AAV-m-SMPD2
Cat No 
AAV-272659
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Smpd2.

AAV-272659
AAV-m-SMPD2

Ready-to-use AAV expressing Mouse Smpd2 (sphingomyelin phosphodiesterase 2, neutral). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AW108287; nSMase; nSMase1
Description (Vector)
Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
Gene ID
20598
Gene Name (Vector)
sphingomyelin phosphodiesterase 2, neutral
Gene Symbol
Smpd2
ORF Size (aa)
1260
ORF Size (bp)
1260 bp
RefSeq ID
NM_009213
RefSeq Synonyms
NM_009213, BC010978,
Species
mouse
UniGene ID
Mm.953

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.