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mouse SMPD2 shRNA silencing AAV

Name 
AAV-m-SMPD2-shRNA
Cat No 
shAAV-272659
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Smpd2.

shAAV-272659
AAV-m-SMPD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Smpd2 (sphingomyelin phosphodiesterase 2, neutral). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AW108287; nSMase; nSMase1
Description (Vector)
Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
Gene ID
20598
Gene Name (Vector)
sphingomyelin phosphodiesterase 2, neutral
Gene Symbol
Smpd2
ORF Size (aa)
1260
ORF Size (bp)
1260 bp
RefSeq ID
NM_009213
RefSeq Synonyms
NM_009213, BC010978,
Species
mouse
UniGene ID
Mm.953

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.