mouse SIRT5 Over-expression AAV

Name 
AAV-m-SIRT5
Cat No 
AAV-272010
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Sirt5.

AAV-272010
AAV-m-SIRT5

Ready-to-use AAV expressing Mouse Sirt5 (sirtuin 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
0610012J09Rik; 1500032M05Rik; AV001953
Description (Vector)
NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.
Gene ID
68346
Gene Name (Vector)
sirtuin 5
Gene Symbol
Sirt5
ORF Size (aa)
567
RefSeq ID
NM_178848
RefSeq Synonyms
NM_178848, BC087898, BC031770,
Species
mouse
UniGene ID
Mm.35325

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.