mouse SIRT2 Over-expression AAV

Name 
AAV-m-SIRT2
Cat No 
AAV-272008
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Sirt2.

AAV-272008
AAV-m-SIRT2

Ready-to-use AAV expressing Mouse Sirt2 (sirtuin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5730427M03Rik; Sir2l; SIR2L2
Description (Vector)
NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA.
Gene ID
64383
Gene Name (Vector)
sirtuin 2
Gene Symbol
Sirt2
ORF Size (aa)
1170
ORF Size (bp)
1170 bp
RefSeq ID
NM_022432
RefSeq Synonyms
NM_022432, NM_001122766, NM_001122765, BC021439,
Species
mouse
UniGene ID
Mm.272443

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.