mouse SCRIB Over-expression AAV

Name 
AAV-m-SCRIB
Cat No 
AAV-271470
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Scrib.

AAV-271470
AAV-m-SCRIB

Ready-to-use AAV expressing Mouse Scrib (scribbled planar cell polarity). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI118201; Crc; CRIB; mKIAA0147; Scrb1; SCRIB1; vartul
Description (Vector)
Scaffold protein involved in different aspects of polarized cells differentiation regulating epithelial and neuronal morphogenesis. Most probably functions in the establishment of apico-basal cell polarity. May function in cell proliferation regulating progression from G1 to S phase and as a positive regulator of apoptosis for instance during acinar morphogenesis of the mammary epithelium. May also function in cell migration and adhesion and hence regulate cell invasion through MAPK signaling. May play a role in exocytosis and in the targeting synaptic vesicles to synapses. Functions as an activator of Rac GTPase activity.
Gene ID
105782
Gene Name (Vector)
scribbled planar cell polarity
Gene Symbol
Scrib
ORF Size (aa)
4839
ORF Size (bp)
4839 bp
RefSeq ID
NM_134089
RefSeq Synonyms
NM_134089, NM_001310543, NM_001310542, BC062888, BC060689,
Species
mouse
UniGene ID
Mm.25568

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.