mouse RNGTT Over-expression AAV

Name
AAV-m-RNGTT

Cat No
AAV-270759

Availability
4-5 weeks

This is an AAV expressing Mouse Rngtt.

AAV-270759

AAV-m-RNGTT

Ready-to-use AAV expressing Mouse Rngtt (RNA guanylyltransferase and 5′-phosphatase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AU020997; HCE; MCE1

Description (Vector)

Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.

Gene ID

24018

Gene Name (Vector)

RNA guanylyltransferase and 5'-phosphatase

Gene Symbol

Rngtt

ORF Size (aa)

1794

ORF Size (bp)

1794 bp

RefSeq ID

NM_011884

RefSeq Synonyms

NM_011884, NM_001305273, BC043657,

Species

mouse

UniGene ID

Mm.464346

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.