mouse PURB Over-expression AAV

Name 
AAV-m-PURB
Cat No 
AAV-269858
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Purb.

AAV-269858
AAV-m-PURB

Ready-to-use AAV expressing Mouse Purb (purine rich element binding protein B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310015K15Rik; AA114818; Cager-2; D11Bwg0414e
Description (Vector)
Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity).
Gene ID
19291
Gene Name (Vector)
purine rich element binding protein B
Gene Symbol
Purb
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_011221
RefSeq Synonyms
NM_011221, BC156317,
Species
mouse
UniGene ID
Mm.474493

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.