mouse PURB shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Purb.
shADV-269858
Ad-m-PURB-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Purb (purine rich element binding protein B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310015K15Rik; AA114818; Cager-2; D11Bwg0414e
Description (Vector)
Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity).
Gene ID
19291
Gene Name (Vector)
purine rich element binding protein B
Gene Symbol
Purb
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_011221
RefSeq Synonyms
NM_011221, BC156317,
Species
mouse
UniGene ID
Mm.474493
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.
