mouse PTPRC Over-expression AAV

Name 
AAV-m-PTPRC
Cat No 
AAV-269814
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ptprc.

AAV-269814
AAV-m-PTPRC

Ready-to-use AAV expressing Mouse Ptprc (protein tyrosine phosphatase, receptor type, C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4; T200
Description (Vector)
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Gene ID
19264
Gene Name (Vector)
protein tyrosine phosphatase, receptor type, C
Gene Symbol
Ptprc
ORF Size (aa)
3459
ORF Size (bp)
3459 bp
RefSeq ID
NM_011210
RefSeq Synonyms
NM_011210, NM_001268286, NM_001111316, BC167212,
Species
mouse
UniGene ID
Mm.391573

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.