mouse PSME3 Over-expression AAV

Name 
AAV-m-PSME3
Cat No 
AAV-269686
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Psme3.

AAV-269686
AAV-m-PSME3

Ready-to-use AAV expressing Mouse Psme3 (proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA410043; AU020960; Ki; pa28g; PA28gamma; REGgamma
Description (Vector)
Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.
Gene ID
19192
Gene Name (Vector)
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
Gene Symbol
Psme3
ORF Size (aa)
765
RefSeq ID
NM_011192
RefSeq Synonyms
NM_011192, BC139818, BC015255,
Species
mouse
UniGene ID
Mm.288477

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.