mouse PNKP Over-expression AAV

Name 
AAV-m-PNKP
Cat No 
AAV-268948
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Pnkp.

AAV-268948
AAV-m-PNKP

Ready-to-use AAV expressing Mouse Pnkp (polynucleotide kinase 3′- phosphatase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1810009G08Rik; PNK
Description (Vector)
Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.
Gene ID
59047
Gene Name (Vector)
polynucleotide kinase 3'- phosphatase
Gene Symbol
Pnkp
ORF Size (aa)
1569
ORF Size (bp)
1569 bp
RefSeq ID
NM_021549
RefSeq Synonyms
NM_021549, NM_001290767, NM_001290766, NM_001290764, BC057659,
Species
mouse
UniGene ID
Mm.238254

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.