mouse NR1H3 Over-expression AAV

Name 
AAV-m-NR1H3
Cat No 
AAV-266035
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Nr1h3.

AAV-266035
AAV-m-NR1H3

Ready-to-use AAV expressing Mouse Nr1h3 (nuclear receptor subfamily 1, group H, member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AU018371; LXR; RLD1; Unr1
Description (Vector)
Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (By similarity).
Gene ID
22259
Gene Name (Vector)
nuclear receptor subfamily 1, group H, member 3
Gene Symbol
Nr1h3
ORF Size (aa)
1338
ORF Size (bp)
1338 bp
RefSeq ID
NM_013839
RefSeq Synonyms
NM_013839, NM_001177730, BC012646,
Species
mouse
UniGene ID
Mm.22690

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.