mouse NMNAT1 Over-expression AAV

Name 
AAV-m-NMNAT1
Cat No 
AAV-265880
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Nmnat1.

AAV-265880
AAV-m-NMNAT1

Ready-to-use AAV expressing Mouse Nmnat1 (nicotinamide nucleotide adenylyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2610529L11Rik; 5730441G13Rik; D4Cole1e; nmnat
Description (Vector)
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following mechanical or toxic insults.
Gene ID
66454
Gene Name (Vector)
nicotinamide nucleotide adenylyltransferase 1
Gene Symbol
Nmnat1
ORF Size (aa)
858
ORF Size (bp)
858 bp
RefSeq ID
NM_133435
RefSeq Synonyms
NM_133435, BC138502, BC138500,
Species
mouse
UniGene ID
Mm.76062

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.