mouse MBNL3 Over-expression AAV

Name
AAV-m-MBNL3

Cat No
AAV-264326

Availability
4-5 weeks

This is an AAV expressing Mouse Mbnl3.

AAV-264326

AAV-m-MBNL3

Ready-to-use AAV expressing Mouse Mbnl3 (muscleblind-like 3 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A530038J18Rik; AI661274; CHCR; E430034C16Rik; MBLX; MBLX39; MBXL

Description (Vector)

Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.

Gene ID

171170

Gene Name (Vector)

muscleblind-like 3 (Drosophila)

Gene Symbol

Mbnl3

ORF Size (aa)

1029

ORF Size (bp)

1029 bp

RefSeq ID

NM_134163

RefSeq Synonyms

NM_134163, NM_001310515, BC057157,

Species

mouse

UniGene ID

Mm.295324

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.