mouse MBD2 Over-expression AAV

Name 
AAV-m-MBD2
Cat No 
AAV-264310
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Mbd2.

AAV-264310
AAV-m-MBD2

Ready-to-use AAV expressing Mouse Mbd2 (methyl-CpG binding domain protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MBD2a
Description (Vector)
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemi-methylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. May enhance the activation of some unmethylated cAMP-responsive promoters.
Gene ID
17191
Gene Name (Vector)
methyl-CpG binding domain protein 2
Gene Symbol
Mbd2
ORF Size (aa)
1245
ORF Size (bp)
1245 bp
RefSeq ID
NM_010773
RefSeq Synonyms
NM_010773, NM_001311071, BC046607,
Species
mouse
UniGene ID
Mm.322

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.