mouse MAGEA6 Over-expression AAV

Name 
AAV-m-MAGEA6
Cat No 
AAV-264100
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Magea6.

AAV-264100
AAV-m-MAGEA6

Ready-to-use AAV expressing Mouse Magea6 (melanoma antigen, family A, 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Mage-a6
Description (Vector)
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.
Gene ID
17142
Gene Name (Vector)
melanoma antigen, family A, 6
Gene Symbol
Magea6
ORF Size (aa)
978
ORF Size (bp)
978 bp
RefSeq ID
NM_020019
RefSeq Synonyms
NM_020019, BC116902, BC109339,
Species
mouse
UniGene ID
Mm.377098

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.