mouse MAGEA6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Magea6.
shAAV-264100
AAV-m-MAGEA6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Magea6 (melanoma antigen, family A, 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Mage-a6
Description (Vector)
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.
Gene ID
17142
Gene Name (Vector)
melanoma antigen, family A, 6
Gene Symbol
Magea6
ORF Size (aa)
978
ORF Size (bp)
978 bp
RefSeq ID
NM_020019
RefSeq Synonyms
NM_020019, BC116902, BC109339,
Species
mouse
UniGene ID
Mm.377098
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.