mouse HAND2 Over-expression AAV

Name 
AAV-m-HAND2
Cat No 
AAV-261098
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Hand2.

AAV-261098
AAV-m-HAND2

Ready-to-use AAV expressing Mouse Hand2 (heart and neural crest derivatives expressed transcript 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI225906; AI661148; bHLHa26; dHAND; Ehand2; Hed; Th2; Thing2
Description (Vector)
Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity).
Gene ID
15111
Gene Name (Vector)
heart and neural crest derivatives expressed transcript 2
Gene Symbol
Hand2
ORF Size (aa)
654
ORF Size (bp)
654 bp
RefSeq ID
NM_010402
RefSeq Synonyms
NM_010402, BC172639,
Species
mouse
UniGene ID
Mm.430844

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.