mouse FOXO3 Over-expression AAV
This is an AAV expressing Mouse Foxo3.
AAV-259591
AAV-m-FOXO3
Ready-to-use AAV expressing Mouse Foxo3 (forkhead box O3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110048B16Rik; 2010203A17Rik; C76856; Fkhr2; FKHRL1; Foxo3a
Description (Vector)
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Gene ID
56484
Gene Name (Vector)
forkhead box O3
Gene Symbol
Foxo3
ORF Size (aa)
2019
ORF Size (bp)
2019 bp
RefSeq ID
NM_019740
RefSeq Synonyms
NM_019740, BC166015,
Species
mouse
UniGene ID
Mm.466459
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.