mouse WAC Over-expression AAV

Name 
AAV-m-WAC
Cat No 
AAV-258422
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Wac.

AAV-258422
AAV-m-WAC

Ready-to-use AAV expressing Mouse Wac (WW domain containing adaptor with coiled-coil). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110067P07Rik; A230035H12Rik; AI256735; AI256776; Wwp4
Description (Vector)
Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway.
Gene ID
225131
Gene Name (Vector)
WW domain containing adaptor with coiled-coil
Gene Symbol
Wac
ORF Size (aa)
1941
ORF Size (bp)
1941 bp
RefSeq ID
NM_153085
RefSeq Synonyms
NM_153085, NM_001282093, NM_001146298, BC080851,
Species
mouse
UniGene ID
Mm.476731

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.