mouse EIF2S1 Over-expression AAV

Name 
AAV-m-EIF2S1
Cat No 
AAV-258193
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Eif2s1.

AAV-258193
AAV-m-EIF2S1

Ready-to-use AAV expressing Mouse Eif2s1 (eukaryotic translation initiation factor 2, subunit 1 alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
0910001O23Rik; 2410026C18Rik; 35kDa; Eif2a; eIF2alpha
Description (Vector)
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Gene ID
13665
Gene Name (Vector)
eukaryotic translation initiation factor 2, subunit 1 alpha
Gene Symbol
Eif2s1
ORF Size (aa)
948
ORF Size (bp)
948 bp
RefSeq ID
NM_026114
RefSeq Synonyms
NM_026114, BC016497, BC016448, BC005463,
Species
mouse
UniGene ID
Mm.196220

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.