mouse DOK1 Over-expression AAV

Name 
AAV-m-DOK1
Cat No 
AAV-257383
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Dok1.

AAV-257383
AAV-m-DOK1

Ready-to-use AAV expressing Mouse Dok1 (docking protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AW557123; p62DOK
Description (Vector)
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Gene ID
13448
Gene Name (Vector)
docking protein 1
Gene Symbol
Dok1
ORF Size (aa)
1449
ORF Size (bp)
1449 bp
RefSeq ID
NM_010070
RefSeq Synonyms
NM_010070, NM_001291799, BC013066,
Species
mouse
UniGene ID
Mm.156

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.