mouse DAPK2 Over-expression AAV

Name 
AAV-m-DAPK2
Cat No 
AAV-256805
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Dapk2.

AAV-256805
AAV-m-DAPK2

Ready-to-use AAV expressing Mouse Dapk2 (death-associated protein kinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation|Function: Isoform 2 can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.
Gene ID
13143
Gene Name (Vector)
death-associated protein kinase 2
Gene Symbol
Dapk2
ORF Size (aa)
1113
ORF Size (bp)
1113 bp
RefSeq ID
NM_010019
RefSeq Synonyms
NM_010019, BC022165,
Species
mouse
UniGene ID
Mm.335252

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.