mouse DACH1 Over-expression AAV

Name 
AAV-m-DACH1
Cat No 
AAV-256782
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Dach1.

AAV-256782
AAV-m-DACH1

Ready-to-use AAV expressing Mouse Dach1 (dachshund 1 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Dac; Dach
Description (Vector)
Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity).
Gene ID
13134
Gene Name (Vector)
dachshund 1 (Drosophila)
Gene Symbol
Dach1
ORF Size (aa)
2100
ORF Size (bp)
2100 bp
RefSeq ID
NM_007826
RefSeq Synonyms
NM_007826, NM_001038610, BC141130,
Species
mouse
UniGene ID
Mm.320593

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.