mouse CITED1 Over-expression AAV

Name 
AAV-m-CITED1
Cat No 
AAV-255522
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cited1.

AAV-255522
AAV-m-CITED1

Ready-to-use AAV expressing Mouse Cited1 (Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI316840; AU019144; Msg1
Description (Vector)
Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
Gene ID
12705
Gene Name (Vector)
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
Gene Symbol
Cited1
ORF Size (aa)
612
RefSeq ID
NM_007709
RefSeq Synonyms
NM_007709, NM_001276474, NM_001276473, NM_001276466, BC052030,
Species
mouse
UniGene ID
Mm.2390

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.