mouse CITED1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Cited1.
shADV-255522
Ad-m-CITED1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cited1 (Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI316840; AU019144; Msg1
Description (Vector)
Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
Gene ID
12705
Gene Name (Vector)
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
Gene Symbol
Cited1
ORF Size (aa)
612
RefSeq ID
NM_007709
RefSeq Synonyms
NM_007709, NM_001276474, NM_001276473, NM_001276466, BC052030,
Species
mouse
UniGene ID
Mm.2390
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.