mouse CCL4 Over-expression AAV

Name 
AAV-m-CCL4
Cat No 
AAV-254840
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ccl4.

AAV-254840
AAV-m-CCL4

Ready-to-use AAV expressing Mouse Ccl4 (chemokine (C-C motif) ligand 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Act-2; AT744.1; MIP-1B; Mip1b; Scya4
Description (Vector)
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
Gene ID
20303
Gene Name (Vector)
chemokine (C-C motif) ligand 4
Gene Symbol
Ccl4
ORF Size (aa)
279
RefSeq ID
NM_013652
RefSeq Synonyms
NM_013652, BC119259, BC119257,
Species
mouse
UniGene ID
Mm.244263

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.