mouse CCL4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ccl4.
shADV-254840
Ad-m-CCL4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ccl4 (chemokine (C-C motif) ligand 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Act-2; AT744.1; MIP-1B; Mip1b; Scya4
Description (Vector)
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
Gene ID
20303
Gene Name (Vector)
chemokine (C-C motif) ligand 4
Gene Symbol
Ccl4
ORF Size (aa)
279
RefSeq ID
NM_013652
RefSeq Synonyms
NM_013652, BC119259, BC119257,
Species
mouse
UniGene ID
Mm.244263
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.