mouse CASP9 Over-expression AAV

Name 
AAV-m-CASP9
Cat No 
AAV-254566
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Casp9.

AAV-254566
AAV-m-CASP9

Ready-to-use AAV expressing Mouse Casp9 (caspase 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI115399; APAF-3; AW493809; CASP-9; Caspase-9; ICE-LAP6; Mch6
Description (Vector)
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP)|Function: Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Gene ID
12371
Gene Name (Vector)
caspase 9
Gene Symbol
Casp9
ORF Size (aa)
1365
ORF Size (bp)
1365 bp
RefSeq ID
NM_015733
RefSeq Synonyms
NM_015733, NM_001277932, BC056447, BC056372,
Species
mouse
UniGene ID
Mm.468800

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.