mouse BRUNOL4 Over-expression AAV

Name 
AAV-m-BRUNOL4
Cat No 
AAV-254099
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Celf4.

AAV-254099
AAV-m-BRUNOL4

Ready-to-use AAV expressing Mouse Celf4 (CUGBP, Elav-like family member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A230070D14Rik; Brul4; BRUNOL-4; Brunol4; C130060B05Rik
Description (Vector)
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Gene ID
108013
Gene Name (Vector)
CUGBP, Elav-like family member 4
Gene Symbol
Celf4
ORF Size (aa)
1458
ORF Size (bp)
1458 bp
RefSeq ID
NM_133195
RefSeq Synonyms
NM_133195, NM_001174074, NM_001146295, NM_001146294, NM_001146293, NM_001146292, BC052744, BC048405,
Species
mouse
UniGene ID
Mm.266435

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.