mouse BMPR2 Over-expression AAV

Name 
AAV-m-BMPR2
Cat No 
AAV-254033
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Bmpr2.

AAV-254033
AAV-m-BMPR2

Ready-to-use AAV expressing Mouse Bmpr2 (bone morphogenetic protein receptor, type II (serine/threonine kinase)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2610024H22Rik; AL117858; AW546137; BB189135; BMP-2; BMPR-2; BMPR-II; BMPRII; BRK-3; Gm20272
Description (Vector)
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
Gene ID
12168
Gene Name (Vector)
bone morphogenetic protein receptor, type II (serine/threonine kinase)
Gene Symbol
Bmpr2
ORF Size (aa)
3117
ORF Size (bp)
3117 bp
RefSeq ID
NM_007561
RefSeq Synonyms
NM_007561, BC156868, BC148339,
Species
mouse
UniGene ID
Mm.391654

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.