mouse BACE1 Over-expression AAV
This is an AAV expressing Mouse Bace1.
AAV-253587
AAV-m-BACE1
Ready-to-use AAV expressing Mouse Bace1 (beta-site APP cleaving enzyme 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ASP2; Bace; C76936
Description (Vector)
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Gene ID
23821
Gene Name (Vector)
beta-site APP cleaving enzyme 1
Gene Symbol
Bace1
ORF Size (aa)
1506
ORF Size (bp)
1506 bp
RefSeq ID
NM_011792
RefSeq Synonyms
NM_011792, NM_001145947, BC048189,
Species
mouse
UniGene ID
Mm.24044
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.