mouse AWAT2 Over-expression AAV

Name 
AAV-m-AWAT2
Cat No 
AAV-253468
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Awat2.

AAV-253468
AAV-m-AWAT2

Ready-to-use AAV expressing Mouse Awat2 (acyl-CoA wax alcohol acyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9430062J17Rik; ARAT; Dgat2l4; WS
Description (Vector)
Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have 2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters; however this activity is unclear in vivo.
Gene ID
245532
Gene Name (Vector)
acyl-CoA wax alcohol acyltransferase 2
Gene Symbol
Awat2
ORF Size (aa)
1002
ORF Size (bp)
1002 bp
RefSeq ID
NM_177746
RefSeq Synonyms
NM_177746, NM_001290395, BC138086, BC138085,
Species
mouse
UniGene ID
Mm.118171

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.