mouse APLP1 Over-expression AAV

Name 
AAV-m-APLP1
Cat No 
AAV-252824
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Aplp1.

AAV-252824
AAV-m-APLP1

Ready-to-use AAV expressing Mouse Aplp1 (amyloid beta (A4) precursor-like protein 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
APLP1 may play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I|Function: The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis (By similarity).
Gene ID
11803
Gene Name (Vector)
amyloid beta (A4) precursor-like protein 1
Gene Symbol
Aplp1
ORF Size (aa)
1965
ORF Size (bp)
1965 bp
RefSeq ID
NM_007467
RefSeq Synonyms
NM_007467, BC021877,
Species
mouse
UniGene ID
Mm.2381

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.