mouse ANAPC2 Over-expression AAV

Name 
AAV-m-ANAPC2
Cat No 
AAV-252599
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Anapc2.

AAV-252599
AAV-m-ANAPC2

Ready-to-use AAV expressing Mouse Anapc2 (anaphase promoting complex subunit 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9230107K09Rik; AL024279; Apc2; Emi4; Imi4; mKIAA1406
Description (Vector)
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.
Gene ID
99152
Gene Name (Vector)
anaphase promoting complex subunit 2
Gene Symbol
Anapc2
ORF Size (aa)
2514
ORF Size (bp)
2514 bp
RefSeq ID
NM_175300
RefSeq Synonyms
NM_175300, BC137583,
Species
mouse
UniGene ID
Mm.291624

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.