mouse ACO1 Over-expression AAV

Name 
AAV-m-ACO1
Cat No 
AAV-251916
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Aco1.

AAV-251916
AAV-m-ACO1

Ready-to-use AAV expressing Mouse Aco1 (aconitase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Aco-1; Irebp; Irp1
Description (Vector)
Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding|Function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity).
Gene ID
11428
Gene Name (Vector)
aconitase 1
Gene Symbol
Aco1
ORF Size (aa)
2670
ORF Size (bp)
2670 bp
RefSeq ID
NM_007386
RefSeq Synonyms
NM_007386, BC005454,
Species
mouse
UniGene ID
Mm.331547

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.