mouse RUNX1 Over-expression AAV

Name 
AAV-m-RUNX1
Cat No 
AAV-250906
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Runx1.

AAV-250906
AAV-m-RUNX1

Ready-to-use AAV expressing Mouse Runx1 (runt related transcription factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AML1; CBF-alpha-2; Cbfa2; Pebp2a2; Pebpa2b
Description (Vector)
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B-dependent transcriptional activation.
Gene ID
12394
Gene Name (Vector)
runt related transcription factor 1
Gene Symbol
Runx1
ORF Size (aa)
1320
ORF Size (bp)
1320 bp
RefSeq ID
NM_009821
RefSeq Synonyms
NM_009821, NM_001111023, NM_001111022, NM_001111021, BC069929,
Species
mouse
UniGene ID
Mm.4081

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.