mouse ABI1 Over-expression AAV

Name 
AAV-m-ABI1
Cat No 
AAV-250583
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Abi1.

AAV-250583
AAV-m-ABI1

Ready-to-use AAV expressing Mouse Abi1 (abl-interactor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
abi-1; E3B1; NAP1; Ssh3bp1
Description (Vector)
ABI1 may act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level (By similarity).
Gene ID
11308
Gene Name (Vector)
abl-interactor 1
Gene Symbol
Abi1
ORF Size (aa)
1431
ORF Size (bp)
1431 bp
RefSeq ID
NM_007380
RefSeq Synonyms
NM_145994, NM_007380, NM_001331045, NM_001331044, NM_001331043, NM_001077193, NM_001077192, NM_001077190, BC079642, BC004657,
Species
mouse
UniGene ID
Mm.205647

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.