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human PRPF40A Over-expression AAV

Name 
AAV-h-PRPF40A
Cat No 
AAV-234450
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PRPF40A.

AAV-234450
AAV-h-PRPF40A

Ready-to-use AAV expressing Human PRPF40A (pre-mRNA processing factor 40 homolog A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
fas ligand-associated factor 1; Fas-ligand associated factor 1; FBP11; FBP-11; FLAF1; FNBP3; formin binding protein 3; formin-binding protein 11; Formin-binding protein 3; HIP10; HIP-10; huntingtin yeast partner A; huntingtin-interacting protein 10; Huntingtin-interacting protein A; HYPA; NY-REN-6; NY-REN-6 antigen; pre-mRNA-processing factor 40 homolog A; Prp40; PRP40 pre-mRNA processing factor 40 homolog A; renal carcinoma antigen NY-REN-6
Description (eCommerce)
Formin-binding protein 11 (FBP11) binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). FBP11 plays a role in the regulation of cell morphology and cytoskeletal organization. It is required in the control of cell shape and migration. It may play a role in cytokinesis and pre-mRNA splicing [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75400].
Gene ID
55660
Gene Name (eCommerce)
pre-mRNA processing factor 40 homolog A
Gene Name (Vector)
pre-mRNA processing factor 40 homolog A
Gene Symbol
PRPF40A
HGNC ID
HGNC:16463
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
649
ORF Size (bp)
649 bp
Protein Name (eCommerce)
Pre-mRNA-processing factor 40 homolog A
RefSeq ID
NM_017892
RefSeq Synonyms
NM_017892, BC027178,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Gene Expression,Immunology,mRNA Processing,mRNA Splicing,RNA Processing
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,immunology,genetics
Species
human
Target Sentence
Formin-binding protein 11 (FBP11) binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). FBP11 plays a role in the regulation of cell morphology and cytoskeletal organization. It is required in the control of cell shape and migration. It may play a role in cytokinesis and pre-mRNA splicing [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75400].
UniProt ID (eCommerce)
O75400

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.