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human TMEM189-UBE2V1 Over-expression AAV

Name 
AAV-h-TMEM189-UBE2V1
Cat No 
AAV-232191
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TMEM189-UBE2V1.

AAV-232191
AAV-h-TMEM189-UBE2V1

Ready-to-use AAV expressing Human TMEM189-UBE2V1 (TMEM189-UBE2V1 readthrough). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CROC-1B; CROC1B; KUA-UEV
Description (Vector)
The TMEM189-UEV mRNA is an infrequent but naturally occurring read-through transcript of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this read-through mRNA and the function of its protein product has not yet been determined.
Gene ID
387522
Gene Name (Vector)
TMEM189-UBE2V1 readthrough
Gene Symbol
TMEM189-UBE2V1
HGNC ID
HGNC:33521
ORF Size (aa)
1113
RefSeq ID
NM_199203
RefSeq Synonyms
NM_199203, BC172339,
Species
human
UniGene ID
Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.