human UGT1A5 Over-expression AAV

Name 
AAV-h-UGT1A5
Cat No 
AAV-230235
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human UGT1A5.

AAV-230235
AAV-h-UGT1A5

Ready-to-use AAV expressing Human UGT1A5 (UDP glucuronosyltransferase family 1 member A5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
UDPGT; UDPGT 1-5; UGT1E
Description (Vector)
UGT1A5 encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. UGT1A5 is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter.
Gene ID
54579
Gene Name (Vector)
UDP glucuronosyltransferase family 1 member A5
Gene Symbol
UGT1A5
HGNC ID
HGNC:12537
ORF Size (aa)
1602
ORF Size (bp)
1602 bp
RefSeq ID
NM_019078
RefSeq Synonyms
NM_019078, BC141470,
Species
human
UniGene ID
Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.